Strengthening Our Connections to Promote Life: A Life Promotion Toolkit by Indigenous Youth was proposed in 2019 to develop a youth-focused and youth-led response to suicide, mental wellness, and substance use in Indigenous communities. A life promotion lens was used in the creation of this guide, which will be presented at the World Indigenous Suicide Prevention Conference. The conference was scheduled for 2020 but was pushed ahead to 2021 due to the COVID-19 pandemic. The theme of the conference is Strength in Our Communities. Originally the guide was to be developed over one year with in-person gatherings, but the Youth Action Group for Life Promotion had to adapt in response to the pandemic, and everything was done virtually.